I’ve been on cymbalta, hydrocodone, duloxetine, buspirone, Gabapentin and methocarbamol at night for over a year and hydrocodone, gabapentin, buspirone in the morning as well. I use Salon Pas patches and Roll-ons and still have nerve zaps , stingers going to the toes, Leg numbness , sciatic and sacrum pain . I had an L4-S1 fusion 4/17/23 and 3 weeks later a friend twisted me while I was seated. Then the next week the nurse practitioner for the surgeon said it might be a set back but you can start lifting , bending, and twisting so I went home and bent over to dry my lower legs and felt a burning that never improved. I just found out a month ago at Mayo I have a screw loose screw and was told to leave it alone. Out of all that the last couple months the best relief I get is a massage about every 3 weeks, pelvic therapy helped, I force myself 3 times a week to walk-in a pool which hurts but to keep my sanity I have to get out and for $3 a visit it is worth it for a heated pool