So far the numbers are borderline. Thank you for suggesting Keith McCormick's book. I'll check it out. The other side effect of Prolia is decreased immunity. I am on the inactive kidney transplant list, and should the need arise to transfer to active status, then this risk factor is also a major consideration. My nephrologist has clearly stated I am not a candidate for bisphosphonates. I am waiting on a second opinion from her before responding to my primary care doctor.