← Return to Prolia and renal failure

Discussion

Prolia and renal failure

Osteoporosis & Bone Health | Last Active: 6 days ago | Replies (16)

Comment receiving replies
@leeleevb

I have been off of it for a year as I am going through an oral bone graft and implant procedures and I am not sure that the bone graft even has taken. I go back December 18th to find out how bone graft did. The oral surgeon insisted that I need get my prolia until it was all complete which could me summer of 2025 and the last prolia shot was 11/2023. I can't take the pill form of anything, but possibly reclast if the doctor would prescribe it, but can it cause osteonecrosis as well and that is why the oral surgeon insisted I not take anything for my osteoporosis until dental procedures complete. Evenity scares me because of heart problems as my dad died of heart disease and it runs in my family.

Jump to this post


Replies to "I have been off of it for a year as I am going through an oral..."

The studies on Evenity showed no difference in cardiovascular risk between Evenity and placebo, and a small difference with alendronate but theory is that might be because alendronate is slightly protective. I have afib and a family history and had no concerns taking Evenity.

Reclast can cause osteonecrosis after 3-5 years, generally, but would probably not be recommended if you are having dental issues and surgery. Evenity in the later months may also cause risk for necrosis to a lesser degree, I have been told.

Forteo and Tymlos do not cause dental issues and may even help with healing but are usually not taken after Prolia because they don't help with rebound and are less effective after Prolia. (My dentist thinks all osteoporosis drugs are a problem but that is not true!)

You have already been off Prolia for a Year. Have you had a DEXA scan or done bone markers, especially CTX, to see what your risk is now?

Seems like getting your surgery done asap and then Evenity or Reclast (depending on your DEXA) might be paths to discuss with your doctor.