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Anyone seen research on long term Proton Pump Inhibitor use and PN?

Neuropathy | Last Active: Dec 10 7:08pm | Replies (18)
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@bigjohnscho

I have taken a PPI (proton pump inhibitor) for many years due to acid reflux. I now have peripheral neuropathy. I recently read that PPI’s over long term can cause neuropathy. Has anyone else experienced this

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Replies to "I have taken a PPI (proton pump inhibitor) for many years due to acid reflux. I..."
Jenny | @fairymystry | Dec 6 4:24am

I've taken Prilosec/Omeprazole for over 21 years and developed idiopathic peripheral neuropathy about 5 or so years ago. I had no idea there was research linking the 2.....

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bigjohnscho | @bigjohnscho | Dec 6 5:19am

How can we find out?

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Spreyton | @furdog | Dec 7 8:56am

Do you have burning feet ?

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djhunt66 | @djhunt66 | Dec 8 1:00am

PPI"s can makr you drficient on B12. Being deficient in B12 is one of the causes of neuropathy. I would have your b12 level checked.

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Colleen Young, Connect Director | @colleenyoung | Dec 8 5:20pm

Also see this related discussion:
- Anyone seen research on long term Proton Pump Inhibitor use and PN?: https://connect.mayoclinic.org/discussion/anyone-seen-research-on-long-term-proton-pump-inhibitor-use-and-pn/

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chrisanon | @chrisanon | Dec 9 5:14pm

PPI's have been shown to cause Drug Induced Lupus. Try plain baking soda- look it up. I use about 1.8th tsp to 1/2 c water. Done with drugs (there are many!) that cause DIL.

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