I also have abscessus with erm41 gene, was MAC before. I was on everyday Arikayce for 10 months the culture became negative at last 2 months treatment, I stopped Arikayce for about 2 months due a big drop of PFT, my sputum turned to positive right after I stopped arikayce. now I am on 3x/week Arikayce for 3 months, still culture positive. I think 3x/week is not enough but I couldn’t tolerate it for everyday. The abscessus is very stubborn.