@hudsonlady many people don't need to start at a low dose of Tymlos. It's fine to start with a full dose or half dose and see how you do. Ramping up with dose adjustments may not eliminate side effects either: for me starting low and moving up on dose made it possible/tolerable to do.

This is not a studied protocol and the company, Radius, is not going to recommend it. Many doctors won't either. I think I brought the idea to the forum a few years back but never intended everyone to do it or to suggest that folks should stay at a lower dose to avoid all side effects.

My doctor has patients do this when necessary rather than quitting- which I almost did! He watched me try to get on various meds over 16 years and was happy that anything helped!

As for instructions: it is very individual. I tried a half dose and has trouble. I went down to two clicks and maybe every week or so went up a click. I ended up at 7 clicks most of the time, and 6 if I had something important to do. Oddly I could never tolerate 8 clicks (I did that maybe three times total in two years).

ps We are all increasing Radius' business since some of us would have quit!!!!