I’m new to all of this so please bear with me. I was diagnosed in January, 2024 with M. abssessus and bronchiectasis accidentally after abnormal chest CT and subsequent BAL. I was asymptomatic until this summer (July I think). Symptoms began with cough, fatigue, night sweats. Infectious Disease and Pulmonary advised early intervention with 3 antibiotics (not sure if they were the “Big 3”) Azithromycin, omadacycline, and linezolid. Due to contraindicated linezolid and current Wellbutrin, and having serotonin syndrome after 2 days, switched to tedizolid. Tedizolid gave me neuropathy in feet after 1 month so it was d/c’d. 2nd BAL showed MAC and inhaled amikacin was added daily to already daily azithromycin and omadacycline. Have had baseline and 1 follow-up hearing test. All good there. Now being advised to add ethambutol with a follow up BAL in 1 month. My concern is this… just in past few days my vision in my right eye has declined so I am unsure about adding ethambutol. I am scheduled for baseline eye exam this week. Not sure what is the vision decline culprit. (To complicate further, I have also been on Wegovy for weight loss and am taking my goal weight maintenance dose.) I feel like I have a good team of doctors but also feel kind of left in the dark as to prognosis, which side effects are concerning for each med (besides the obvious vision, hearing and neuropathy, not to mention the torturous serotonin syndrome I experienced). There are so many overlapping effects and I feel miserable. I don’t feel like I have gotten enough education on expectations, prognosis, and risk/benefits of this multi drug therapy. I asked my ID doctor if this were his own wife would he be recommending such treatment. Yes was his answer. I just don’t know enough to even know whether to continue to treat and just suck it up for the 12-24 months or what the alternatives even are. If it makes any difference I am a 55 year-old female ex-smoker for over 20 years. If you’ve read this far, thank you. Any and all feedback appreciated.