← Return to Began Tymlos 4 wks ago; flying solo till I see Endo in 3wks... advice?

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@gently

windyshores,
I'm not thinking there will ever be such a link. No one will conduct studies.
The FDA approved Tymlos on the basis of one clinical trial. The suspicion of osteosarcoma was directed from the Forteo rats and the two year limit was because of that caution. It remains in the Forteo insert that Forteo should only be given for more than two years in select patients likely to benefit, i.e., those with high fracture risk.
One doctor told me that the third year is similar to off label use, another said that he almost never prescribes medicines as recommended in inserts. He thinks the doses are often too high for women of little weight.

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Replies to "windyshores, I'm not thinking there will ever be such a link. No one will conduct studies...."

@gently the point is that Forteo is allowed for more than 2 years (Lilly did a study) as described below- but Tymlos isn't.:
2.3 Recommended Treatment Duration
Use of FORTEO for more than 2 years during a patient’s lifetime should only be considered if a patient remains at or has
returned to having a high risk for fracture [see Warnings and Precautions (5.1)].

Again, the two year limit has not been lifted for Tymlos.

If anyone has a doctor prescribing Tymlos for more than two years, I would love to read about it.