← Return to Reclast Risk of Atrial Fibrillation with Mitral Valve Regurgitation

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@gently

spiderplant, the best answers come from the experienced members. From pubmed:

Contrastingly, some studies indicate that BPs are antiarrhythmic by inhibiting fibrotic myocardial remodeling.

[P]ossible mechanisms [for afib with bisphosphonates] include antiangionesis-related myocardial remodeling, calcium handling abnormalities, and inflammatory changes.
https://nyaspubs.onlinelibrary.wiley.com/doi/10.1111/nyas14332
https://pmc.ncbi.nlm.nih.gov/articles/PMC8820972/

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Replies to "spiderplant, the best answers come from the experienced members. From pubmed: Contrastingly, some studies indicate that..."

@genlty hmmmm that study on bisphosphonates and afib was January 2022. I was hoping it was older and outdated! My endo told me that that risk had been disproven so now I have to talk with him. So far I have had two 1mg doses of Reclast (20% dose) and I am going to talk to him about the third, especially since Ben Leder MD says a half dose may be enough. That said, in my case, more fractures could be life-threatening and I seem to be able to deal with afib when it happens by going to the ER. I haven't had any since I went on Reclast and had two whole years without afib while on Tymlos despite the fact that it sped up the heart briefly.