← Return to Began Tymlos 4 wks ago; flying solo till I see Endo in 3wks... advice?

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@windyshores

@annie208 at -2.6, with a margin of error of -.5, your femur neck's bone density is not terrible. and is right on the line. It is true that people with osteopenia also fracture, of course, but since your fall was traumatic, it is unclear whether the fracture was due to osteoporosis.

The same thing happened to me in 2006. Horrendous fall on icy steps, landed on my back on the corner of concrete steps and had 3 fractured vertebrae. The excellent endocrinologist told me that the fractures were very likely not due to osteoporosis (I think I was borderline like you) but with a fracture, we qualify for insurance coverage of anabolic drugs.

If you can tolerate 8 clicks all the better. I ramped up but never expected to be entirely without side effects. IF you stay on 8 clicks the issues may resolve- or if they don't, 7 clicks is great!

I barely gave any thought to my bones in your situation. It was only 5 years on cancer meds that made my bones worthy of attention! Other than your femur neck you are in good shape. But you are relatively young so being on top of things the way you are is smart.

I injected in my abdomen because, with a kid with type 1 diabetes, I knew that absorption there is better and faster than any other site. That said I requested thigh for Evenity injections because I had a horrible reaction to the fast absorption in tummy.

A P1NP after one month may not be a baseline. I have no idea how long it takes for Tymlos to raise P1NP. I had my P1NP done at 18 months which seemed to suggest that it was no longer doing much at that point. I continued for 6 more months while I decided what to do next, and both doctors suggested I do that, as did McCormick.

My well-respected endo does not use bone markers and says they do not tell the whole story about what is going on in bones. McCormick says they need to be done properly (CTX early in am, fasting, and at a consistent time). My endo says an entire conference could be held on this question. I have kidney disease which affects CTX. This dilemma seems unresolvable. I sporadically ask my PCP to order bone markers and then talk to McCormick, but I am as skeptical of him as I am of any other provider! (I have talked with McCormick for 18 years and seen my endo for the same period...)

Again, your fracture may or may not be osteoporotic, but since you have a fracture, you can do Tymlos and even Evenity with insurance coverage. You are getting that ho hum reaction from doctors because they see people with multiple non-traumatic fractures (me!) and severe DEXA scores. Hope you are feeling better these days after surgery!

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Replies to "@annie208 at -2.6, with a margin of error of -.5, your femur neck's bone density is..."

@windyshores, I'm curious at your observation of the margin of error on the T-score being .5. I've never seen that reported; I'd like to learn more, can you site a source? .5 is a pretty big margin...