We would all love for strontium to be researched more, but with the advent of strontium via ranelate there is lots of research. Probably more research than for most other osteoporosis drugs.Plus there are several studies including one old one by the USA army on just strontium and on strontium via citrate.
No one is saying that 680mg of strontium daily is not a therapeutic dose level. You have to have a therapeutic dose to supply the amount of strontium needed to bridge holes in our bones which then allows calcium to adhere and for bone to grow. Dentists, brain surgeons, bone doctors are all using strontium infused products when they need to grow bone. Dang, the original sensodyne toothpaste still found outside the USA uses strontium in its toothpaste.
TBS and REMs are proving that people who have only DEXA do have improved bones with strontium. The dexa argument of 10% skew is lacking in the face of more than a 10% growth in bone density and in the back up results of rems and tbs which say that the bone density and bone quality are good for strontium users. Dang, according to TBS, strontium users are in the top three of bone quality results. And if that isn't enough we have the biopsies of strontium users bones.
The strontium via ranelate cessation was in Europe briefly for strontium ranelate; the company says it never was based on a ban, but the population study which caused all the concern was a study that has been unable to be reproduced by anyone, and Denmark tried for a year. I wouldn't base my drug or supplement decisions on a population study that can not be reproduced. But I would also never take strontium via ranelate; it has aspartame in it and that is just too concerning an additive to me and tied to too many problems in many research studies not just one flawed population study.
That shows one of the problems with trying to make money off of natural products. In order to patent natural products you must tack on a man made product or a man made delivery. Then you skew insurance where it only pays for the patented pharma med and not the compounded med. If you have to have the insured product I woud at least try to go with the natural product using a patented delivery device and research it extensively to try and maintain safety.