I can't comment on which is best after chemo, unfortunately, but I think it's safe to trust your oncologist's recommendation for any of the -lutamides.

Sadly, the big pharma companies are slow getting their drugs approved in Canada -- they focus first on big markets like the EU and U.S., and leave us for the second round -- so we often lag a couple of years. Apalutamide has been in the Ontario drug formulary since 2022 (I needed special approval to start on it in 2021); Pfizer got Health Canada approval for Orgovyx only at the very end of 2023, and it's not in the Ontario formulary yet (which is weird, because it's priced exactly the same as Firmagon, at about CA $315 == US $225 / month). I don't know what the status of Darolutamide is.