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Chemotherapy ...Scared

Prostate Cancer | Last Active: Dec 8 12:37pm | Replies (25)

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@northoftheborder

@melcanada Apalutamide is much newer than Zytega, and the "-lutamides" in general are a bit like miracle drugs for some cancer situations (that may or may not apply to yours).

Apalutamide is also, unfortunately, very expensive. In Canada, it costs nearly CA $5,000 (US $3,500)/month; in the U.S., it can cost 4 or 5 times that much. Ontario did add Apalutamide to the formulary in early 2022, so it's covered by the Ontario Drug Plan, the Trillium Drug Benefit, and most private insurers. There's also a patient-access programme that your oncology team might be able to enroll you in, if there's some issue with coverage.

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Replies to "@melcanada Apalutamide is much newer than Zytega, and the "-lutamides" in general are a bit like..."

Darolutamide is even Newer than Apalutamide And has fewer side effects. In the US it cost about $12,000 a month but insurance pays almost all of that. I’m on Medicare And this year the maximum you can pay is $2000 for all your drugs. This year I paid $2300 in January and then never paid anymore for any drugs for the rest of the year. That’s how Medicare works.

There is a reason you go on Zytiga before lutamides. If you go on Zytiga first You can then go on one of the lutamides and have a good chance that it will work for another few years. It doesn’t work in the reverse, Going from a lutamide to Zytiga Almost always fails.

I went from 2.5 Years of Zytiga To Darolutamide And now after a little over a year I’ve been undetectable for a year. With Zytiga I was undetectable for one month in that 2 1/2 years And my PSA kept jumping all over the place

There’s a link to an article in the Lancet about The best sequence of using the Drugs.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30688-6/abstract?mc_cid=c2dca8aa74&mc_eid=99575fc699

We have full coverage $ Wife at Ministry, plus OHIP at 80 years senior Thanks
Is it Darolutamide not the best after Chemo and all else I have been on?

App is Erleady