Jan 2022, age 72, Stage 4 BC spread to a few bones and C3 vertebrae. 5 sessions radiation took care of the bones. Then I took Ribociclib 600 for 19 days and nearly collapsed in a train station due to neutropenia. 2-3 weeks later tried 400. After 9 days sharp pain in head so I quit it but not soon enough. My liver enzymes AST and ALT shot up near 1200. I was hospitalized for 10 days for 24/7 infusions. The only drug that brought the numbers down was a steroid which left me with side effects I’m still dealing with today. I deeply regret taking the Ribociclib. I took letrole from Feb - June 2022. Now I’m supposed to take it everyday but I don’t want the effects of not enough estrogen to brain and bones etc. Eventually I learned about the Metabolic Therapy for cancer which makes more sense to me. So I’m focused on that.
These are hard decisions and all the oncologists are not on the same page when they discuss these dangerous drugs.