I had the middle section and tail of pancreas removed during my surgery in 2022. I took Creon 36k 3x per day for about 7 months and then I got in the donut hole of Medicare and had a very large copay do I tried papaya enzymes (otc at Mother’s Market and they worked just as well and then I didn’t have them with me sometimes, but found I could eat just as well without them. According to post by @stageivsurvivor most? or all of the digestive enzymes are located in the head of the pancreas. Another post on this thread someone mentions that their dr says it takes for the pancreas digestive system to “wake up” after surgery so I guess that’s what happened to me.