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@jwoy

My husband had his first Lupron injection on Oct 15th. Started Zytiga a week later. No side effects at all until 3 weeks in. Then bam, soaking night sweats and big time fatigue. Care team started him on 100 mg Gabapentin to help with night sweats. Very helpful. Maybe a couple since starting that, but not nearly as bad. But, fatigue is still an issue, plus he started radiation 11/25, for 20 days.

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Replies to "My husband had his first Lupron injection on Oct 15th. Started Zytiga a week later. No..."

A fan in the bedroom with a remote control is a game-changer for hot flushes at night. You can get a good floor fan on a stand for well under $100, and he can use the remote to turn it on and off as needed without getting out of bed.

A doctor at one of the conferences I attended recently said that he reduced the fatigue by increasing the prednisone from 5 mg to 7 1/2 mg. I know someone else that increased it to 10 mg and it worked for them. Ask your doctor.

Getting a lot of exercise is supposed to help in reducing the fatigue as well. Weight training and walking daily can really help, and they also offset the deterioration of your muscles that occurs when you’re on Zytiga and Lupron.