The shrinkage was on the ILC tumor. From 2.9 cm to 1 cm. Initial dosage was 3 tablets of Ribociclib for 21 days then rest for 7 days. After that you have to resume the dosage. This is taken with 2.5 mg of Letrozole. But three months after I had a nasty case of diarrhea, some hair loss and fatigue. I experienced itchiness in my arms and legs too. My oncologist reduced the dosage to two tablets of Ribo per day. The diarrhea, fatigue and the itchiness stopped but the mild hair loss is still there. I have been taking it since May and will continue until April 2025.