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Possible PSSD symptoms

Depression & Anxiety | Last Active: Mar 13, 2022 | Replies (45)

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@lisalucier

Hi, @jbp26 - welcome to Mayo Clinic Connect. That sounds like a very challenging journey, with the horrendous withdrawal from citalopram with crushing depression and loss of sex drive. Glad to hear that escitalopram has now helped with your anxiety and depression.

Hoping that @challen will return with some input, and also hoping that @merpreb @jakedduck1 @gailb and @parus may have some input for you.

So, with the buproprion (Wellbutrin) and the supplements you mentioned, has your post-SSRI sexual dysfunction (PSSD) improved? Have you considered going to a specialist in sexual dysfunction who might have more familiarity with this condition?

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Replies to "Hi, @jbp26 - welcome to Mayo Clinic Connect. That sounds like a very challenging journey, with..."

Wellbutrin and other dopamine supplements have essentially cured my symptoms of anhedonia and brain fog. I'm productive and can enjoy things again. They have helped with PSSD to an extent. I can have sex but it can be difficult for me to stay engaged mentally. I don't have feelings of passion or desire. Before this, I could easily have sex every day and would get frustrated and irritable if I went a day or two without. Now, it doesn't really matter.

I saw a sex therapist for a while, but it wasn't much help. I think my problem is physiological. I have seen several psychiatrists, but most of them don't believe that what I experienced is possible. I have been considering seeing an endocrinologist as a next step. I haven't searched for any doctors specializing in sexual dysfunction but that is a good idea.

I would also like to welcome you to Connect @jbp26 . I'm sorry that you are having so much trouble. Many SSRI's lower or diminish sexual drive. After you stop taking it should eventually come back, I've been told. Is your withdrawal from citalopram guided by a physician or are you doing this by yourself? If your withdrawal side effects have been horrendous than that would lower your sexual desires too.