Prescribed Tymlos after Evenity

@mayblin Thanks. Yes, I had bone markers done prior to starting Tymlos. I'm not going to sweat any of this. I knew from the get-go that this process could continue to be very stressful and that was going to be the worst possible thing for my physical and mental health. There's no way I'm going back to that, and I appreciate that I got a little taste of it last week to remind me to refocus myself and commit to a calm and positive mindset.

@hollygs you seem to know what you are doing! Hope you can stay on Tymlos. We seem to be forced to do things that aren't completely studied yet (including things studied only in rats!)- if we can find doctors who will help us with that.

@gently thanks on the rats! I got carried away by that study because I have been so concerned that my "own protocol" = as two endos put it) of doing Evenity after Tymlos would somehow cancel out my gains on Tymlos. But yes, rat studies are not going to push things forward for us as yet 🙂

@windyshores Best wishes to you!

Hi @windyshores , this is exact conversation I was looking for. I been struggling with my back pain for over 7 months now. I am on Evenity. Two doctors suggested Tymlos after and information is very conflicting. It’s not much research done on the subject. I been finding various answers- from yes, you can go on Tymlos after Evenity with 2 months break in between. I also found information that no need to wait 2 months- just one. All this is very confusing. My endocrinologist didn’t respond to my email where I asked him very same question. I am not sure if my pain is from Evenity or from old fractures, posture and very weak bones. I probably have to finish Evenity. I hate not be able to move so much. I still trying to do a few exercises and eat food loaded with calcium and taking vitamin D , magnesium. My husband bought treadmill for the home since he is not able to walk with me everyday. I will start walking more everyday. I installed an app curable health but not sure if this is going help me because pain is none stop, except for a 2-3 hours in the morning. I would like to read someone’s experience who doing or did Tymlos after Evenity . I don’t have a lot of choices with my -5.1 T score. I have to build bone first in order to move on any other medication which supports what already build. ( sorry for mistakes - I am writing through the sever pain).

@sunnny65 awww so sorry for your pain. My doctor said Evenity takes time to mineralize and said I should start Reclast with a two month break after Evenity,
if that helps.

I feel stiffer on Evenity and Reclast and did not feel that on Tymlos, but these things are subjective so cannot be sure.

Hi @sunny65. I hope you don't mind me chiming in here. First of all, I'm so sorry that you're having such a rough time. I hope you've discussed your pain with your medical team. It would probably be a good idea to consult with a pain management specialist if that hasn't happened yet. If you're concerned about what your treatment plan will be moving forward, it sounds like you might want to reach out to your endo again. I don't know if you saw this whole thread to which you replied, so if not, you can search "Prescribed Tymlos after Evenity." That's my current situation, and I got some great replies. If you have any questions for me, please do feel free to reach out here. Best wishes to you.

Hello @hollygs . Thank you so much for your kindness and reply. Yes, I am in a very tough situation. Never expected nothing like this. I been working with pain specialist and he tried a few things which all failed and made me worse. My pain is none stop and all my medical team don’t offer anything but Tramadol and now Norco ( I didn’t take this yet). But Tramadol doesn’t work anymore. I never took anything like this before and it makes my stomach very upset. My hands are shaking and I really don’t know where this all is going. My endocrinologist told me that I can start Tymlos right after finishing Evenity. I was looking for information everywhere and not much studies done. The most doctors offering the opposite. Tymlos and then Evenity. I been searching if anyone in this group has any experience with this kind of sequence. Thanks God you wrote to me. My -5.1 T score is very scary. Please tell me how soon you started Tymlos after Evenity and what was the outcome. It is very hard to live with this pain. I was very active and outgoing and for the past 7 months I stopped going anywhere except doctor’s appointments and this is very sad and depressing. Thanks again for any advice and input.

According to my doctor, 6-8 weeks wait after Evenity for another drug.

And I was told I could stop Evenity early since it is not anabolic the whole time.

I hope you can discuss with your doctor!

@hollygs Reading thru your post and all the comments I don't see anything about bone scans. Are you getting DXAs or Echolight scans to track what results you are getting with the different meds?
If you are getting scans and have one at beginning and end of Evenity and one at the beginning of Tymlos (I guess that's the same as the end of Evenity?) then you can get another scan now and know exactly how you are doing on Tymlos. There's no absolute magic about waiting a year (other than insurance and money) for a scan. I've twice paid for DXAs rather than waiting till the year was up, because I wanted the information right away to make decisions about what I'm doing with my osteo treatment.

Others have given you good info on your situation. I agree that there is currently no research to show what happens following Evenity with Tymlos.
I could not find any. My guess is that it would work. But that is nothing but a guess.
A few months ago when I was researching this I was interested in following that sequence myself. I gave it up because I just couldn't find any evidence to support that path. I thought it likely that it would work but I did not want to chose a sequence with no evidence supporting it.

I searched the various osteoporosis forums trying to find people who were following Evenity with Tymlos or Forteo. I found 3-4 people who were doing or about to do that on their doctors recommendation. No one had completed a year on the follow up med and none had a scan yet to see the results.
I found an interview where Dr Michael Lewiecki a noted osteo doctor, mentioned that he had had one patient do that with success. He gave no further relevant details on that one case.
So if you have a baseline DXA scans and you get another DXA you may be our first test case. I'm guessing and hoping you will be successful.