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DiscussionWhat to bridge when tapering off effexor
Depression & Anxiety | Last Active: 2 hours ago | Replies (8)Comment receiving replies
Replies to "Yes and she has done this the previous two times I tried unsuccessfully so I insisted..."
Found this on ZocDoc:
"Tapering is something of a hot topic among psychiatrists, and prevailing opinion in the field is changing. For years, it’s been standard for doctors to recommend 2-4 week tapering regimens. But two psychiatric researchers recently published a paper recommending an “extended tapering regimen, reducing [a patient’s] dosage by smaller and smaller increments, down to one-fortieth of the original amount.” This method takes months or even years, but researchers say it accounts for how antidepressants change brain chemistry, while the old way does not."
I also saw reference to the fact that it can be harder to go from 2mg to 1mg than from 20mg to 10mg. In other words the end of the taper needs to go even more slowly and use a liquid.
One article mentioned that Prozac's half life is 2-4 days. Effexor is 5-10 hours. According t that article the shorter the half life, the longer the taper needs to be. One person mentioned being put on Prozac at the end of a taper of Zoloft but it wasn't clear what the timing of that was.
I am so glad to see so much more info on withdrawal online. When my family member was coming off, there wasn't much at all!