I can relate to the issue with the side effects! I will mention that when I tried Tirosint I had an extreme reaction….I thought I was having a stroke! I was told to stop it immediately and within a few days I felt much better. Considering how long it takes for the medication to get into my system, the immediate improvement after stopping it made me think I had an intolerance to their formula. When I changed Endocrinologists, the doctor wanted to try Tirosint again and attributed my issue with the pill form; he stated, “You did not try the liquid version.” I tried the liquid version and shortly after starting I started having the bad reactions again and once again I had to stop taking it and immediately felt better. When I was researching Tirosint, I noticed several posts about needing a much lower dose due to it’s lack of fillers and my dose had been the same as my Synthroid so maybe that was why the reaction was so severe.
I take one medicine so any side effects would be related to whatever I am currently prescribed. As of now, the 50mcg of Levoxyl 5 days a week seems to have the least of the negative side effects. I just started splitting the days off from medication, to see if this helps. I have an appointment to go over my results next week so I will see if I can reduce it further or if I need to go to 6 days a week. One of the odd things with my side effects is that I seem to have more symptoms of Hyperthyroidism, yet I have Hypothyroidism. Since I have 1/2 of my thyroid my hope is that it will pick up the slack and I can manage with the lowest dose possible to minimize side effects.
If you are taking several medications, maybe the issue isn’t the changes in the thyroid medication but a change in one of your medications….maybe they changed what they use for filler. There is a compatibility site on the internet where you can put in your medications to see if they are compatible. The side effects associated with some very common medications could be playing off each other. I recently had a meal with Soy Beans and then felt extreme weakness and tiredness ….I had forgotten about the impact of Soy on thyroid. So many variables when you have an issue with side effects!
Since you took your medications for a long time without issues, I would tend to think it might be a change in the formula that caused the issues for you. I have a long history of side effects with medications, as did my father and Grandmother, so I tend to think it’s related to my history. On a good note, it motivates me to use old fashioned remedies for common ailments! Good luck!