Thank you for sharing your story. I had very early detection, a lumpectomy, and 5 rounds of radiation, with clear margins and nodes. My oncologist prescribed anastrozole, and after 3 months, I have stopped taking it. My Dr. mentioned only the weight gain. He didn't warn me about the other possible side effects. Mine in particular, became a crippling depression, not wanting to get out of bed, crying every day. My body aching so badly I can't stand up straight when I first get out of bed. I don't know if I will go back on it, but I know I can't keep going with these powerful side effects. Foggy brain, total loss of libido. And yes, weight gain. I have a follow up appt. with the Dr. in one month. I wonder if the alternative drugs are as bad? This is the first time I have been on a forum like this, and I really appreciate reading everyone's story. Thank you!