Side effects of Letrozole

Posted by mjmac @mjmac, 1 day ago

Has anyone out had weird muscle reactions while on Letrozole. Ab area muscles in particular. I’ve had a CT of pelvic & Abdomen and they found nothing unusual.

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Did you type letrozole in the search bar above? I know people have issues. I have been on it 2.5 years with no side effects.

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I found certain generics had additives that caused a reaction. Letrozole made by Accord gave me shooting pains across my shoulders and upper chest. The pills were pink so perhaps it was the colorant used as I've had issues with colorants in other meds and products. I found I had the least side-effects with Letrozole by Teva (light yellow pill). 2nd choice was Letrozole made by Breckenridge. I finished my 5 years in May so I don't know what pharma options are available now. Out of 5 pharmacies in my town, only 1 pharmacist would work with me and special order Letrozole from Teva (Pharmacist at local Walmart.) Most stores only work with their contracted supplier for generics. So you may need to call around if your current pharmacy will not change prescription to another manufacturer of Letrozole.
Hang in there and good luck.

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They made me ache and feel like I was 100 years old I could barely get out of a chair. I tried 3 different ones all had the same side effects.

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@georga35

I found certain generics had additives that caused a reaction. Letrozole made by Accord gave me shooting pains across my shoulders and upper chest. The pills were pink so perhaps it was the colorant used as I've had issues with colorants in other meds and products. I found I had the least side-effects with Letrozole by Teva (light yellow pill). 2nd choice was Letrozole made by Breckenridge. I finished my 5 years in May so I don't know what pharma options are available now. Out of 5 pharmacies in my town, only 1 pharmacist would work with me and special order Letrozole from Teva (Pharmacist at local Walmart.) Most stores only work with their contracted supplier for generics. So you may need to call around if your current pharmacy will not change prescription to another manufacturer of Letrozole.
Hang in there and good luck.

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FYI, my Letrozole pills from Accord are Not pink. They are a yellow orange.
Interesting why they would be different in color 🧐
Are you in the USA?

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@jeanadair123

They made me ache and feel like I was 100 years old I could barely get out of a chair. I tried 3 different ones all had the same side effects.

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Exactly how I feel. My hands are especially wrecked. My body is in constant pain.

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@judydarlene

FYI, my Letrozole pills from Accord are Not pink. They are a yellow orange.
Interesting why they would be different in color 🧐
Are you in the USA?

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Yes, I'm in the states. It was a few years ago but I remember the color change when I picked up the prescription and made the tech double-check the manufacturer source with the pharmacist. It was Accord and not Teva. Anyway, I had told my oncologist about the concern about additives/changes between generics. He said he had several other patients report similar issues. I finally got him to write 'Teva' as preferred source on prescription renewal.

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Thanks for clarifying. And thanks for your prompt response:)

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@jnorki

Exactly how I feel. My hands are especially wrecked. My body is in constant pain.

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I just couldn’t handle it anymore.
One just hopes they made the right move but it was quality of life I put first.

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I'm sorry. I just had a visit with my oncologist and have decided to stop the Letrozole until mid January and see how I feel about switching to a different medicine. I two days free of the letrozole but have read it could take weeks to feel better. I am also wondering if the neuropathy I have in my hands is permanent? My finger tips have no feeling other than pins and needles 24x7.

Are you feeling better and if so, how long after stopping Letrozole did it take for improvement?

Thanks for sharing.

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After only 2 weeks my eyesight was blurry. I was told by dry eyes and to stop talking Letrozole and everything would return to normal in a couple of days. That was 4 months ago and no better. Even after using prescribed eye drops every 2 hours. I used to be able to read a newspaper and do crosswords and suduko, now cannot read a paper or accurately get the numbers and letters in the squares of puzzles. Have new glasses but they don't work either. Head optometrist checked and prescription correct. I see ophthalmologist specialist next week and would like some information to present to him

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