@umeshghimire

You wrote "retroperoneal area". Would you mean retroperitoneal? You are asking about chemotherapy treatment protocol. Do you have access to the pathology report? It is the pathologist (physician) who examines tissue and specimens under the microscope and provides a diagnosis of the kind of cancer. Peritoneal refers to the location (the tissue that is the lining for the wall of the abdomen) but not the type of cancer cells that the pathologist writes about in their report.

It sounds like cancer was found from lymph node biopsy and then in the peritoneal area. The doctors believe that there is a primary cancer somewhere else but they haven't located it. Is that correct? They are treating your wife's cancer as if it is a "secondary cancer" meaning the cancer may have originated somewhere else.

Here is a link that describes cancers related to the peritoneum:

MD Anderson: Peritoneal Cancer

-- https://www.mdanderson.org/cancerwise/peritoneal-cancer--8-questions--answered.h00-159697545.html

Is your wife interested in getting another opinion? If yes, here is a link to the National Cancer Institute's NCI) Designated Cancer Centers. You might like to look through this page and locate the NCI closest to where you reside. These centers have ongoing research and clinical trials.

NCI-Designated Cancer Cancer Centers:

-- https://www.cancer.gov/research/infrastructure/cancer-centers

Do my questions, resources, and comments help?