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Low IgG and low IgA

Autoimmune Diseases | Last Active: 14 hours ago | Replies (11)
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@catartist

No myaloma - yet - as I do have MGus. Is that a possible connection I am not aware of!? I too take Prednisone daily ( 35 years) for Asthma first and then RA for 30 years ( can’t get lower than 5 mg now). Also biologic IV for RA ( and others). Fun isn’t it!?

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Replies to "No myaloma - yet - as I do have MGus. Is that a possible connection I..."
kayabbott | @kayabbott | 16 hours ago

I have had IgA kappa MGUS for 8 years (I'm 70). Some people have IgG or IgM and/or Lambda MGUS. My IgG and IgM levels are very low but my IgA inflammation is elevated. There is a 1% risk per year of MGUS progressing to smoldering multiple myeloma (SMM) or to MM, so pretty low. MGUS is a waiting game, mostly checking bloodwork a few times a year to see changes in the Kappa, Lambda, and various other markers. It would be good to get more info from your doctor on your MGUS and IgG, IgA.

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