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← Return to Your PSA Trends after Salvage Radiation & 6 Months of Orgovyx?
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Your PSA Trends after Salvage Radiation & 6 Months of Orgovyx?
Prostate Cancer | Last Active: Nov 24, 2024 | Replies (13)Comment receiving replies
I finished 33 Salvage Radiation Treatments in July/22 and my PSA continues to be undetectable at < .008 Unfortunately my testosterone level is also almost undetectable but I was still able to win my squash match this evening. I have had incontinence issues ever since my RP in 2018 and throughout 2023 I was leaking approximately 200 grams per day. Suddenly in January 2024 my average urine weight jumped to 300 grams per day and I have just been informed that increased incontinence issues can arise 6, 12, or 18 months after the salvage radiation.
Replies to "I finished 33 Salvage Radiation Treatments in July/22 and my PSA continues to be undetectable at..."
it took about five years after salvage radiation before my incontinence problem started. It has gotten progressively worse since then. Getting a physical therapist that specializes in incontinence could help. There are a lot of treatments that a urologist that specializes in the incontinence can suggest you try Bulkamid, a sling, ProAct and more.
I had RP in 10/21 and had the usual initial incontinence which gradually improved over the next year. I had gotten to where I didn't need a pad sleeping or at home and could play a round of golf walking and not have any significant leakage in a very light Tena pad.
As part of my treatment for rising PSA in last Q of 2022, I had triple therapy followed by 37 pelvic radiation treatments in April/May 2023. My incontinence has gradually increased since and I have been forced to wear a pad 24/7 and completely soak a light absorbency pad playing golf.
The good news is my PSA has remained undetectable (even with ultra sensitive assay) since my second chemo treatment in Nov 2022. My MO stopped my Darolutamide at the end of my 3 months of chemo and took me off Lupron after one year (last injection was 7/23). My T has failed to return to anywhere near normal levels (52 earlier this month). My MO has referred me to an endocrinologist to begin TRT. He said I am a 90 year old man living in a 70 year old body without T. From his extensive experience (>500 publications on prostate cancer and related topics, 30 years treating this disease, Director of prostate cancer research at Hopkins etc) he believes my aggressive cancer clones have been killed and if my PSA rises on the TRT it can be controlled.
I realize this is a controversial approach. It is not for everyone. It depends on extent of disease, response to treatment, type of treatment, etc etc. I begin my TRT next week and am looking forward to feeling like myself again. The fatigue, muscle loss (despite exercise), diminished libido, depression-all side effects from the very low T, have been difficult to endure. I will be interested to see if my incontinence improves as I continue to do core/kegel exercises and the T helps strengthen these muscles.
Good luck to everyone fighting this beast.
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Were you on ADT at any time?