← Return to Ductal cancer Gleason score of 8 Radiation/hormone therapy or surger

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@heavyphil

My own two cents on this, as a layman who has had Gleason 4+3 return after 5 yrs, is to have the surgery, go on ADT immediately and start radiation as soon as the RO feels your surgical recovery is complete.
Yes, it is probably the most aggressive treatment in terms of duration, but an aggressive cancer WILL come back and if it was ME in your shoes I would want to hit it as hard as possible at the outset…why waste precious time? Best of luck with whatever you decide

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Replies to "My own two cents on this, as a layman who has had Gleason 4+3 return after..."

If the PSMA shows no spread beyond the prostate, which is the situation here, why would you recommend going to radiation as soon as surgical recovery is complete? Where are they going to radiate? My surgeon was very clear on this- they would not under any circumstances recommend I begin radiation and put me on ADT until they can actually see evidence of biochemical recurrence. Otherwise they are literally shooting in the dark. If there is a 20-30% chance you will not have a BCR, they will not put you through these kinds of very highly aggressive treatments with all of their potentially major side effects until the evidence shows that you indeed have a BCR, or in other words, until the chances you won't have a BCR go to zero.