@lilacs777 It might be good to keep in mind that Reclast and other bisphosphonates have a recommended limit of 3-5 years.

I was not able to do Reclast during my 5 years of letrozole even though I already had osteoporosis, because my endo was afraid of triggering afib (I already had it every once in awhile, and this risk has been disproven since) and kidney disease.

I did lose bone and did fracture- after treatment was done, mainly because COVID interfered with going on Tymlos in time. I did two years of Tymlos and my bones are now better than before cancer, but that may be an unusual gain.

I think the answer will depend on your DEXA scores. Doctors aren't prescribing for osteopenia anymore and some people aren't doing meds for early/mild osteoporosis. All the meds have time limits and they add up so that those of us who have done a lot of them run out!

The other concern with not doing Reclast or Zometa (both zoledronic acid) is that they are not thought to be beneficial for preventing spread of cancer. That is something to discuss with your oncologist.