Most people tolerate them well. The ones who don't are more likely to talk about it, so it may seem to you like the drugs are riskier than they are. You have no way to know what group you'll be in until you start taking it. Way I see it, you don't have a choice ; you need to try something.

@goseve with 7 spinal fractures I am here to say that for me those fractures have been a lot worse than any side effect.

I got on Tymlos by starting at a low dose. The pen has "clicks" that measure dosing. If you are afraid you could talk to your doctor about trying that but get yourself up to a good dose as quickly as possible.

People seem to have few side effects on Evenity in my circle of friends. Ditto Reclast. But they are not on the forum!

Don't know how typical my case is, since 'typical' doesn't really seem to apply to all this, does it? I've been on Tymlos only two weeks and I have the same side effect pretty much every night within an hour or so of the injection: very mild lightheadedness, which isn't constant but comes and goes through the night. When I get up in the morning it's gone. I do the injection betw 7 and 8 pm when I'm just sitting around doing nothing, so I'm not really hindered by the lightheadedness. Maybe if I was more active it would be a problem. I do hope I habituate to it, but if not, it's tolerable. I've also noticed more aches and pains in my hips and lower back. Wrists and thumbs, too. My arthritis has waxed and waned over the years so I can't say these are from the Tymlos, tho they are listed as possible side effects. So far, and considering the benefit I'm hoping to get, I'd say the inconvenience from side effects rates a 2 out of 10 on the kvetch scale. Keep in mind, if you start Tymlos and find you can't tolerate it, you can stop.