Intraductal Prostate Cancer: Any info about recurrence rates?
Anyone on here have intraductal prostate cancer and low Gleason? I was diagnosed this year and had surgery. Gleason 3+4 and clear pathology except intraductal. Doctors just say follow up PSAs which have been thankfully, undetectable. However I am not understanding future reoccurrence rate and which medications/treatments I will need. Anyone on this forum with intraductal?
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I’m supposed to get a link to the conference itself so people can watch it again. I will post that link here when I get it.’
Here is a link to the place where the conference will be posted. It is part of the journal club. There are a number of other very interesting conferences there already.
https://www.urotoday.com/video-lectures/a-journal-club-for-patients-with-prostate-cancer.html
@biker70 here’s the invitation I received for the UCSF seminar they discussed problems with intraductal and cribriform.
How does one reconcile a biopsy core of 4+3 with cribriform present with a low (.40) Decipher score?
Follow your PSA monthly. You don’t mention latest PSA or your Gleason score Need to know that and what you’ve had done, what medicine/treatment you’re on now in order to really give opinions. .
I am 4+3 and have had it for 15 years. 4 reoccurrences so far. Still, I have treatments to move to in the future.
As @jeffmarc indicates, some of it has to do with the size of the cribiform glands. Are they greater than .25mm? If so, that seems to be a negative feature based on studies. On my pathology, and I think many other people’s, the size of the cribiform glands is not listed. I’m also a 4+3. 10% of my pattern 4 is cribiform, which seems kind of in the middle from what I’ve read. In my case, my uPSA is < 0.006, so that is all that matters for now, 13 months post-surgery. I do know, however, that my recurrence odds are higher because of the cribiform.
Gleason is 4+3=7 with crib pattern present (in one core). PSA 4.99. Set for RP in a month. Decipher .40.
Your numbers do not look too bad, but cribriform Is a problem. It causes the Gleason to actually be more aggressive. Here is a video that discusses cribriform, you might want to watch it, it can give you more information.
https://www.urotoday.com/video-lectures/a-journal-club-for-patients-with-prostate-cancer/video/mediaitem/4452-unfavorable-histology-classification-aims-to-reduce-unnecessary-treatment-journal-club-jesse-mckenney-cornelia-ding.html
Thanks for the video. Very interesting.
My path report does not state the size of the cribriform (large or small).
Speak to your doctor. Ask if the slides can be reviewed again to get the size of the cribriform. They may have to send it to a specialist. Depends on where you’re getting your medical treatment.