They can definitely affect our quality of life. I wish there was another way to reduce our risks of relapse, sadly this is what we have now. I still believe it is better than what was available in the past, my grandmother just had to cross her fingers. Sometimes people do better on one drug than another, even a different manufacturer of the same drug will make a difference.
Did you talk to your doctor about possibly try a different endocrine therapy?

I've been on anastrazole for over 1 month and I just stop taking because of my swollen ankles among othe effets.