There are five Rx pancrealipase products in the US with Creon being the most frequently prescribed. The others are Zenpep, Viokace, Pertzye and Pancreaze. There are many OTC brands but they are not enteric coated for timed release and the lipase enzyme activity which is the most important enzyme is significantly less than in the RX versions. The two most recommended OTC brands by Registered Dietitians are Vital Nutrients and Digest Gold.