@beebe I was advised to stop Estradiol (vaginal) after I was diagnosed with endometrial (endometroid adenocarcinoma, Grade 1, Stage 1a) that was estrogen positive. That was five years ago. The Estradiol worked very well for me and my gynecologist told me (and reading scientific articles confirmed) that vaginal estrogen is safe because so little of it is actually absorbed within the blood stream. It is applied topically. Anyway, after diagnosis that all changed. I now use a product recommended by my radiation oncologist. It is only sold online and is on the expensive side but it works for me.

Hyalo-Gyn

-- https://hyalogyn.com/products/hyalo-gyn-suppositories-30-day-supply

I like to use the suppositories because they are less messy. There are other good products that you can purchase in your local stores such as Target. I was advised to use a product that contains hyaluronic acid. Here is another product I have used and still use externally (to the vulva):

Good Clean Love BioNourish Ultra Moisturizing Vaginal Gel with Hyaluronic Acid

-- https://goodcleanlove.com/collections/best-sellers/products/bionourish%C2%AE-ultra-moisturizing-vaginal-gel-with-hyaluronic-acid-assortment?variant=42220336218296