I have had exactly what your doctor is recommending. Once the PSA hits .2 after a prostatectomy, they really need to do salvage radiation to try and kill whatever residual cancer is in the area of the prostate bed I had seven weeks of radiation 3 1/2 years after my surgery when my PSA started rising. I had no side effects from that treatment. Some people get a little fatigue after the sessions. I never had that. My PSA stayed undetectable for 2 1/2 years after having radiation. Results vary some people are completely cured by the radiation. Your Gleason score gives you an idea about whether or not it will come back.

I’m surprised they are starting with Nubeqa. I was on Orgovyx and nubeqa for over a year and it works very well. The thing is they normally start you on Zytiga and when it fails, move you to Nubeqa. That gives a longer path to recurrence. One reason they would not put you on Zytiga is that you have heart issues, in that case Zytiga is not a good drug for you.

One advantage of Nubeqa is that has very few side effects.

I’m getting a Zometa infusion in a couple of days. It’s works like xofigo. These are bone straightening agents. They don’t really prevent mets. Orgovyx will weaken bones and cause osteoporosis. You want to take these drugs to prevent it? Xofigo has a slightly higher risk of osteonecrosis, of the jaw, than zofigo, which is why my oncologist prefers it. When I first started taking Lupron a drug just like Orgovyx my doctor put me on Fosamax, which works almost the same as Xofigo. It’s a pill you take once a week. I saw a seminar a couple of weeks ago where a doctor discussed problems with the bones caused by Lupron and he emphasizes that it is essential to take drugs like Xofigo, fosamax or Zometa to prevent bone weakening.

Orgovyx has a lot of side effects. Hot flashes, brain fog, fatigue and more. If you have issues, come back with questions and people can help..