I've been on the Big 3 every day for 6 years and the Clofazimine every day for a little over a year. I initially started the inhaled Arikayce every day for the first couple years but was able to decrease it to 3 times a week. I also nebulize Levalbuterol then hypertonic saline solution twice a day. I also Mycobacterium Avium Intracellure also. I had a 10 cm cavity grow in my upper left lobe within a month or 2 before starting the antibiotics. Once I started all the meds and up to now, it has shrunk to 4 cm.