@meryw Welcome to Mayo Clinic Connect. It is difficult to hear when someone you care about makes a comment that is upsetting to you. You mention bipolar; is that a condition you have been professionally diagnosed with? If so, are you working with a medical professional and taking any medication?

Perhaps her choice of wording could be different. Instead of just saying something is nuts, could she have said the behavior is nuts? Would that have had less of an impact from the beginning? If so, speaking to her and asking she give you a full idea of what she is reacting to may lessen the impact. It seems to me that oftentimes, people may not fully understand the impact of their words. The tone of voice, choice, place they are spoken, even their body language as they speak, are things we key in on. Is calling you/your behavior manic a new thing with her?
Ginger