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How much pain to tolerate

Polymyalgia Rheumatica (PMR) | Last Active: 1 day ago | Replies (24)

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@brooklyn1947

I started Methotrexate & was feeling pretty good after 3 weeks, so my Dr had me taper off from 5 mg in AM & PM to 5 in AM, but 2.5 in PM. He wanted to increase my Methotrexate, but my blood work showed a slight elevation in my Liver. I started having a lot of discomfort, so I had to go up to 5 in AM & PM.
I am not a happy camper!

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Replies to "I started Methotrexate & was feeling pretty good after 3 weeks, so my Dr had me..."

When I got to 10, my taper became 1 per month. Dropping 2.5 at that point seems to be a bit much.
I tapered at 1 down to 5, and now at 0.5 per month.
I have not had any serious issues on this schedule. Some transient osteoarthritis issues, but nothing I cannot live with. Good luck finding what is right for you.

To brooklyn1947
Forgot to mention that I have not ever split the prednisone dose. There seem to be pros and cons about that.
From others…Splitting the dose seems to keep the pain down, but that might actually reduce the prompts to the adrenals to get back in the business of producing cortisol.