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Salvage radiation therapy after radical prostatectomy

Prostate Cancer | Last Active: Nov 13 8:13am | Replies (90)

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@michaelcharles

I had Salvage Treatment to the WPRT and pelvic lymph nodes together with a short-term of ADT Feb - June 2023; substantially similar to ARM 3 of the SPPORT trial.
My uPSA results since have been < .02, undetectable, with the (dreaded) next 3 mo test next week.
The ADT Orgovyx was not pleasant, however my RO strongly recommended it for the statistical result benefit.
Surgery at age 72 in Aug 2022 confirmed Gleason 9, and postop pathology identified EPE, although I had clean surgical margins, lymph nodes and seminal vesicles. Postop PSA was .19, so my PSA was "persistent" postop, and I promptly followed up with salvage treatment.
2 friends had similar tx with 6 mos ADT.
All 3 of us at Johns Hopkins.
Clearly my hope and prayers are that the salvage treatment effectively killed the escaped PCa cells and that I will have years of freedom from progression. Of course, only time will tell.
Best wishes for you and your treatment decisions.

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Replies to "I had Salvage Treatment to the WPRT and pelvic lymph nodes together with a short-term of..."

Wish you all the best and freedom from progression.
May I ask how did you find Salvage radiation therapy? Did you have any side effects?
Best Regards

Sounds like you made the best decisions possible. With Gleason 9, EPE and persistent PSA, ADT + WPRT is definitely a wise decisions. John Hopkins is an excellent center, you were in good hands. Having clean lymph nodes post op definitely increases your chances your salvage treatment was successful.