There is no doubt in my mind that it can. I'm no expert, but there is a limit to how much stress, abuse, antagonism, etc. our bodies can handle. There is a point when we can no longer cope. This point is different for everyone. Our life experiences have a major effect on this. I submit to you that these experiences begin before we are born. The quality of care our mothers provide for themselves (and therefore us), the health risks they take against themselves (and us), the emotional and/or physical trauma they endure during the pregnancy all influence who we are and how we cope, not to mention our post utero experiences, which include our upbringing and how we were treated by people in our lives. Feelings of hopelessness arise when we are unable to resolve the conflicts in our lives arising from our interactions with others. These feelings lead to chemical imbalances in our central nervous systems, often requiring medication to adjust, hopefully giving us the ability to cope with things we have no control over. At best, people don't care how their actions negatively affect those around them. In fact, many take pleasure in antagonizing others. Many of us grew up with such behavior from our own family members. Ber a person. Don't be people.