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Reclast side effects

Osteoporosis & Bone Health | Last Active: 6 days ago | Replies (321)

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@windyshores

@paula630 I thought Reclast increases bone density. It seems like semantics on the part of the doc who said it doesn't "grow bone." Right? Yes, it is not anabolic. It is anti-resorptive and increases density by lowering turnover. As I am sure you know.

from drugs.com "After treatment with Reclast, BMD increased by 11% from baseline after one year of treatment and by 20.7% from baseline after two years of treatment."

Here is what the doc may have been referring to:
ExcretionUrine (39% ± 16% as unchanged drug) within 24 hours; feces (< 3%)
Half-Life Elimination Triphasic; Terminal: 146 hours
so yeah techically it is "eliminated" relatively quickly but stays around for a long time in bone...

So technically Reclast is "elminated" fairly quickly (via urine) but remains in bone for years and is slowly released. Again the doctor's comments seem like semantics.
From drugs.com:
Zoledronic acid, which is the active ingredient in Reclast, can remain in your body for weeks or years after your last dose1. Reclast is an effective treatment and should improve bone density for around 2-3 years after a person stops treatment2. Side effects such as bone, joint, or musculoskeletal pain may occur days, months, or years after starting therapy3.

I have read somewhere that it can last 10 years. I am not sure. Ask the doc!

I have been concerned about osteoarthritis and bone spurs getting worse on Reclast and especially Evenity but not sure that is studied. Please share if you find anything. Time will tell. Most of the drug info sites mention spinal and joint pain. I have two autoimmune diseases and tend to have a lot of side effects.

Bur for many it is helpful and doesn't have bad side effects. Unfortunately we need it or Fosamax after other meds.

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Replies to "@paula630 I thought Reclast increases bone density. It seems like semantics on the part of the..."

We all know that some people love Reclast. But some people are really harmed by it. Those who are harmed don't need to hear the success stories. It's like the guy who is in the middle of the lake and he has a big hole in his boat and it's sinking fast. He's doomed. And the people on the shore are all calling out to him and telling him how they saved themselves. "We're about to throw some steaks on the grill and drink a cold one. Too bad you can't join us," they say as he sinks into the bottom of the lake.

@windyshores Thamks so much for all the information you provided - and to everyone here. Certainly gives me comfort having a support group like this. I should have results by Monday and doctor follow-up soon after. Now I feel more knowledgeable and will be ready with some questions.
I truly do feel my doctor has been a partner in my journey. When my torn rotator cuff surgery was stopped because my bones “were like butter,” this doctor (endocrinologist) prescribed Tymlos (for 2 years) as well as discussed diet and supplements. After the 2 yrs, I had a successful Rotator cuff surgery and that’s when we moved over to Reclast. Started with 1/2 dose year 1; next year had full dose; due to have dose 3 in 2025. But, as mentioned, broken wrist with a black ice fall, and Dr suggested getting a “booster” 6 mos early. I thought a booster would be half dose, busy they gave me full. That was in August and here we are.
Stay tuned for test results and Thanks to all for listening.