I did try decaf. My result was disliking the taste and thinking why drink it all all then? Both decaf and “None at all” had no impact on my Neuropathy. I was also still a bit fatigued, so I added back 2 cups of coffee each morning. I’m not convinced at all that I have more energy, but it’s a part of my routine I haven’t seen help or hurt my Neuropathy. I don’t drink or eat any other caffeine during the day except for an occasional bite of chocolate. About the only thing in my diet that I find might have an effect on me is the amount of sugar I consume, even though I’m not diabetic. We all respond differently to things!