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Fracture while on Forteo

Osteoporosis & Bone Health | Last Active: Nov 6 9:26am | Replies (6)

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@mayblin

While both estrogen and raloxifene are mild-moderate antiresorptives and could serve as a good add-on in this situation, the known 1-2% risk of venous thrombosis for raloxifene is concerning to older population. On the contrary, transdermal patches of estradiol (bioequivalent) does not share that particular concern. Furthermore, estrogen, with its many regulatory effects on bone health, is known to help with all skeletal sites! An individualized assessment for cvd risk and breast cancer risk is needed for hrt usage for sure.

@drsuefowler your ctx of 1414 after 6mo of fracture is unusual. What's your baseline ctx?

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Replies to "While both estrogen and raloxifene are mild-moderate antiresorptives and could serve as a good add-on in..."

My CTX was 519 the first time I had it measured. That was after being on only 20mcg of Tymlos for about a month. That's all I have to use as a baseline. I wanted Estrogen, but my endocrinologist was against it. He thinks that at 74, I am too old for Estrogen. Interesting that transdermal patches of Estradiol are safer than Raloxifene for getting blood clots. I know I would feel better on Estogen than on Raloxifene. Thanks for your response @mayblin.