My husband is 58 and was diagnosed in Sep of this year, he had a large tumor removed , about 97%, he is going into his fourth week of radiation, and is taking the TMZ , he has had a good deal of constipation with it but no other significant symptoms. He was offered optics therapy while continuing TMZ today by his oncologist. We are interested to hear your responses to the questions posed above in order to make the right decision for us.