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diagnosed with a high calcium score of 1350

Heart & Blood Health | Last Active: Nov 3 11:16am | Replies (25)
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@missey

I am very surprised that he did not prescribe Repatha epiPen! With the combination of a estimbe. My score was 306. I could not tolerate statins at all. This medication has been fantastic and my LDL is now 40! Did he do a lab test for LPA and also for APOB?… LPA is a marker for familial genetic cholesterol problems and APOB (Aloprotein )is a better marker for heart, disease, stroke, etc. than the cholesterol number. Did he also prescribed you to do a stress test or a Doppler with contrast dye to get the picture of your heart and how your blood vessels are faring? Did he prescribed blood pressure medicine?

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Replies to "I am very surprised that he did not prescribe Repatha epiPen! With the combination of a..."
mayoconnectuser1 | @mayoconnectuser1 | Nov 1 7:47am

My reading indicates statins are first line meds, then if intolerance other options are considered - and, since 1000 was already on a statin (although lipid numbers not provided), increasing dosage would normally be next.

1000 - consider advanced lipids panel fir far more info, stress test with echo, peripheral artery scans.

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kisu | @kisu | Nov 2 9:30pm

I'm waiting for Praulent insurance authorization. May I ask your cost for Praulent? I have a high CAC score and will be getting a stress test/dye next week. My APOE 3/4 allele is probably responsible for my CAC score. My Lp(a) is 115.2 nmol/L, and APOB 91. Since Lp(a) is an independent factor, taking a statin, exercising or dieting will not reduce it, and taking a higher statin can increase your Lp(a) by up to 20%. Cardiologists say Lp(a) is not a plaque burden molecule it's a plaque de-stabilizer and mostly related to the Carotid artery, not CAC scores. I told my Cardiologist I wanted a CIMT (carotid intima-media thickness) sonogram. He said he had no idea where I could get one. PCSK9's reduces Lp(a) up to 32% and LDL up to 70%. siRNA (Leqvio) Can reduce Lp(a) up to 90% and up to 50% for LDL.

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