Anyone taken Evinity without side affects

Posted by dreamjean1958 @dreamjean1958, Feb 14, 2023

I have a very severe case of Osteriporosis . WS on Forteo a yr . After being on Forteo. Your suppose to be put on a maintainence. I never was . My surgeon out of network. Prescribed Forteo. 2018 . I took for 13 months . My spine Dr . Or someone dropped the ball. I took calcium and Vit D 3 . My bones are now super bad . No medication was prescribed . I have fractured my foot twice in 2022 . 3 months apart. Still in a cast . Has anyone been prescribed Forteo ? Than didn’t get the drugs to maintain bone strength . I’m so upset. A yr of injections and beings the ball was dropped . I’m back at Day 1 . I’m assuming I will be prescribed EVinity . I’m a walking China Doll . Scared to take any of these meds .

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@windyshores

After Evenity alendronate might be okay. After Prolia I have been told that Reclast is better because it coats the bones more effectively. What does your doctor suggest? I cannot take alendronate due to GERD/reflux but if I could, I would also feel better about shorter term meds.

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After Evenity, he suggests Reclast or Prolia. I will not take prolia but would consider Reclast.
However, as stated above, I would prefer alendronate vs reclast due to "possible" side effects and how long it stays in your system. I'm just curious if alendronate is equally effective in maintaining gains vs Reclast? Bioidentical HRT is also making a lot of sense to me but of course no real studies on this post the botched WHI study. I have some time to continue research and to decide (post anabolic) if I could ever definitively decide between Tymlos and Evenity!!
I am doing the "Starting Strength" program and am really enjoying it and getting stronger (without injuries or soreness) due to attention to good form when lifting. This is similar to the Onero lifting program with research to back this up. But you must have someone who knows how to keep you safe by teaching you excellent form. That is absolute key!

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@osteoresearch

After Evenity, he suggests Reclast or Prolia. I will not take prolia but would consider Reclast.
However, as stated above, I would prefer alendronate vs reclast due to "possible" side effects and how long it stays in your system. I'm just curious if alendronate is equally effective in maintaining gains vs Reclast? Bioidentical HRT is also making a lot of sense to me but of course no real studies on this post the botched WHI study. I have some time to continue research and to decide (post anabolic) if I could ever definitively decide between Tymlos and Evenity!!
I am doing the "Starting Strength" program and am really enjoying it and getting stronger (without injuries or soreness) due to attention to good form when lifting. This is similar to the Onero lifting program with research to back this up. But you must have someone who knows how to keep you safe by teaching you excellent form. That is absolute key!

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@osteoresearch why not do Tymlos then Evenity? Depending on how bad your scores are. Maybe one is enough for you.

Since Evenity is anti-resorptive in the last months it seems reasonable, hypothetically, to do alendronate afterward. Maybe by the time you finish, there will be more info! I would do alendronate if I didn't have GERD.

You can try to use bone markers like CTX and P1NP to assess. My endo doesn't do them but I ask my PCP to order and then talk to Keith McCormick, the author of "Great Bones," who does consultations.

McCormick did Forteo way back when and then alendronate.

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@osteoresearch

I’m curious if alendronate has a lot less side effects vs reclast? And is it equally effective? I start evenity end of Nov. I think I would feel better about daily/weekly dosing vs all at once infusion. Thoughts? Results on alendronate from those of you who chose this route? Also considering HRT post Evenity…..

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I can't have artificial hormones due to concern with blood clots as I'm positive for prothrombin factor X. I do Alendronate once a week and so far, so good. My dr. gave me the choice of reclast infusion or the Alendronate and I did not want the huge infusion. Time will tell how effective it is.

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@gurine

I can't have artificial hormones due to concern with blood clots as I'm positive for prothrombin factor X. I do Alendronate once a week and so far, so good. My dr. gave me the choice of reclast infusion or the Alendronate and I did not want the huge infusion. Time will tell how effective it is.

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I hope the Alendronate works well for you. Keep us posted.

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@windyshores

@osteoresearch why not do Tymlos then Evenity? Depending on how bad your scores are. Maybe one is enough for you.

Since Evenity is anti-resorptive in the last months it seems reasonable, hypothetically, to do alendronate afterward. Maybe by the time you finish, there will be more info! I would do alendronate if I didn't have GERD.

You can try to use bone markers like CTX and P1NP to assess. My endo doesn't do them but I ask my PCP to order and then talk to Keith McCormick, the author of "Great Bones," who does consultations.

McCormick did Forteo way back when and then alendronate.

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My scores are -3.3 avg in spine (lowest number -3.0 L2) and -2.8 in hip. I have one fracture at L2.
First I had decided Tymlos, then back to Evenity, and yes now back leaning toward Tymlos then Evenity, to buy myself more time with anabolics. But I could feel differently next week! My only hesitation with Tymlos was the cancer scare with my previous squamous cell cancer.
Obviously, I'm not "thrilled" to take any of them. I would like to consult with Kevin McCormick but I've already done so many tests I don't really want to repeat them all. But...I may try calling today to see what they need before a consult. I know I will try an anabolic -Tymlos or Evenity - remains the question. I wanted to add this slide from Onero talk which is one reason I was leaning toward Evenity for highest gains in my spine.

Shared files

meds (meds.pdf)

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@osteoresearch that chart confirms why I did Tymlos first and then topped off with Evenity (I only did the anabolic 4 months). I had nasty breast cancer and had no concerns about Tymlos. Granted there was really no way to know if there was any metastasis somewhere.

McCormick didn't look at all the labs he had requested, with me. I would just send him DEXA's , bone markers if you have them, D3 and calcium levels, and info on fracture. Don't go through the stress of meeting all those requirements. Your scores aren't terrible but you have a fracture and with me, since I have fractures, he just discussed meds and not supplements. It's not rocket science!

You may not need two meds to get you out of osteoporosis but you could possibly achieve an even better target with both. Many seem to be starting with Evenity so that is certainly an option. My scores were worse than yours so I needed longer time on anabolics.

ps L2 at -3.0 was your highest number, not your lowest 🙂

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@windyshores

@osteoresearch that chart confirms why I did Tymlos first and then topped off with Evenity (I only did the anabolic 4 months). I had nasty breast cancer and had no concerns about Tymlos. Granted there was really no way to know if there was any metastasis somewhere.

McCormick didn't look at all the labs he had requested, with me. I would just send him DEXA's , bone markers if you have them, D3 and calcium levels, and info on fracture. Don't go through the stress of meeting all those requirements. Your scores aren't terrible but you have a fracture and with me, since I have fractures, he just discussed meds and not supplements. It's not rocket science!

You may not need two meds to get you out of osteoporosis but you could possibly achieve an even better target with both. Many seem to be starting with Evenity so that is certainly an option. My scores were worse than yours so I needed longer time on anabolics.

ps L2 at -3.0 was your highest number, not your lowest 🙂

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Thank you windyshores! I am compiling reports to send to McCormick. Looks like they are scheduling into Dec. currently. Actually meant to type -3.9 at L2 ( site of fracture) not -3.0.

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As I have read many of the comments here and learned a lot, I realized that my doctor knows me best. She has my history in front of her.
She has been urging me to do something about my osteoporosis which started as osteopenia for years before I met her . I am not a "drugs" type of person, so I did all of the natural approaches and held off until I hit the -3.5 in my dexa.
Then I listened and researched!
She halfheartedly recommended Evenity for 12 months followed by a Reclast infusion. When I said yes she was stunned!
After my 4th set of shots which are now (since my last terrible experience--two excruciating shots!) given by RNs, I am doing fine. After my meeting with the PA, who was doing a check up on my progress and wanted to answer my ton of questions, I feel more at peace with my choices. A concern that stood out was why didn't they check my CTX and P1NP. She said that currently they only use those markers with Prolia, Tymlos etc.
She assured me that they have been using Reclast for years and have a very small percentage of patients with long term problems.
Again, I think that it is so important to have a Doctor that knows you and your record (and your temperament!)

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@osteoresearch

Thank you windyshores! I am compiling reports to send to McCormick. Looks like they are scheduling into Dec. currently. Actually meant to type -3.9 at L2 ( site of fracture) not -3.0.

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@osteoresearch big difference -3.9 vs -3.0! With that score and a fracture I wouldn't put too much effort in info he is asking for. He will just say you need meds ! I put a lot of effort into sending info and I don't think he looked at it.

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@gmom14

As I have read many of the comments here and learned a lot, I realized that my doctor knows me best. She has my history in front of her.
She has been urging me to do something about my osteoporosis which started as osteopenia for years before I met her . I am not a "drugs" type of person, so I did all of the natural approaches and held off until I hit the -3.5 in my dexa.
Then I listened and researched!
She halfheartedly recommended Evenity for 12 months followed by a Reclast infusion. When I said yes she was stunned!
After my 4th set of shots which are now (since my last terrible experience--two excruciating shots!) given by RNs, I am doing fine. After my meeting with the PA, who was doing a check up on my progress and wanted to answer my ton of questions, I feel more at peace with my choices. A concern that stood out was why didn't they check my CTX and P1NP. She said that currently they only use those markers with Prolia, Tymlos etc.
She assured me that they have been using Reclast for years and have a very small percentage of patients with long term problems.
Again, I think that it is so important to have a Doctor that knows you and your record (and your temperament!)

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I see that some things I wrote were probably confusing! My Dr. "halfheartedly" recommended meds because she was discouraged with my lack of trust in her previous recommendations. She had already called to establish the complete coverage of the Evenity and follow up with Reclast!
And, yes, my 4th set of Evenity shots were given at the new infusion center...much better experience!

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