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@steve74kooczx

Honestly I don’t know how a body could. My husband started out fine. He was diagnosed with lung Ca with bone metastasis. He had NO signs or symptoms other than a sore back which wouldn’t feel better. I said, “you better go see the Dr”. Of course he didn’t because had an appt for his annual checkup in a few months. Big mistake. That cancer is having a field day!
Nothing on his blood test which was taken later was abnormal except the alkaline phosphatase at 400+. So this lead to an X-ray, which lead to an MRI, which finally lead a PET scan. OMG! The results showed cancer everywhere! He even had 2 fractured vertebrae which had to be surgically fixed with glue.
It’s not like he was immediately started on radiation either…we kept wondering when ? Then it was 2 weeks of radiation and he finally had to use 2 canes for walking. This is a man that took care of 3.5 acre as now sits, the weeds are growing. He used to be so active and his beautiful muscular legs are gone, he’s so little. He’s taking oral chemo, but can only tolerate 1/2 the dosage. He does walk a lot. That’s also becoming less with time.
I’ve read about this cancer. You can be born with this gene! And never know it. I thought if anything he would get skin Ca from working outside in the sun here in FL for 45 years.

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Replies to "Honestly I don’t know how a body could. My husband started out fine. He was diagnosed..."

Welcome to Mayo Connect @steve74kooczx. I'm so sorry to hear about your husband's struggles. I hope he's at a low point only to begin showing some improvement soon. Lung cancer can be very aggressive, and some of the targeted therapies can also be very effective. My story includes blissfully biking around Key West in February 2020, and then not being able to walk around the block back home by the end of April. I am fortunate to have an oral therapy that has been a good match for my mutation, and fortunate that I tolerate the therapy fairly well too. I agree, I wouldn't have been surprised at a different cancer, but lung cancer took me off guard. Sadly, we've all learned that anyone with lungs can get lung cancer.
You mention that he's on an oral chemo and his cancer is likely from one of the gene mutations. The need to reduce a dose isn't unusual and it can be just as effective. With as widespread as the cancer appears to have been, it may take some time to see improvement.
If you don't mind sharing, which mutation does he have (mine is ALK)? and which drug is he taking?