I was in the Responsive Zone for 2+ years. I am now in the Resistant Zone, started up Oct 23, so I've been in the Resistant Zone for slightly over a year. Both my oncologist aren't worried. We did a PSMA Pet Scan last month, I went from a zillion glowing spots to 9 spots so that's good. I feel great. My local oncologist referred me to radiation to radiate a couple of spine spots. Follow your bliss and may the force be with you.