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Has anyone else moved from Firmagon to Orgovyx?
Prostate Cancer | Last Active: Nov 3 7:33pm | Replies (19)Comment receiving replies
After nine years on Firmagon, I recently moved to Lupron which reduced the number of shots required per year as well as the immediate ill after effects of these. Having said this, as it is thought that Lupron isn’t as heart friendly, nor does it make me feel as well overall as when I used Firmagon, I was ready to return to the dreaded monthly shots to my abdomen, that is until I discovered Orgovyx on the Internet. After discussions with my oncologist, I’m about to start this next week and hoping that I will feel as good as I did on Firmagon, albeit without the shot every 28 days and the two to three days I felt quite unwell after each one. I should mention that I also take Enzalutimide every day and have done so for the last seven years. PS In 2013 and at age 62, I was diagnosed with inoperable Stage 4 PC, Gleason Score 9 with painful bone metastases. It made for a pretty bleak outlook but with God’s blessing, terrific doctors along with novel medications as well as a few supplements, I’ve managed to be here to welcome 4 grand daughters, now all under 4 years of age. My retirement has been far from what I’d had once hoped for, but certainly better than the alternative and for this, I try to remember to give thanks each and every day.
Replies to "After nine years on Firmagon, I recently moved to Lupron which reduced the number of shots..."
I took Orgovyx and while "ADT Sucks" , I think from my experience and posts on this site that it is as good as it gets. And I am grateful for ADT medication to help me in my PCa battle.
Sincere best wishes.
Hello, scaramouche,
I am just into my second month on Orgovyx. My biggest problem with Orgovyx has been constipation. I had pre-existing chronic constipation and the Orgovyx has made it considerably worse, plus I seem to have stomach cramping and pain, which may or may not be related to the increased constipation. But the good news is no hot flashes, no big loss of energy, no weight gain, no breast enlargement, no suicidal thoughts, etc. I have had pretty minor, and intermittent, joint pain, muscle pain, and restless leg syndrome (at night). From what others have experienced, my side-effects could be much worse. Best of luck to you!
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I've been three years on ADT + Apalutamide with bone mets as well, starting at age 56. The first 2½ years I was on Firmagon for the ADT, then I switched to Orgovyx (Relugolix) last spring.
Even though Orgovyx is essentially the same thing as Firmagon — a GnRH receptor antagonist — I've noticed a huge improvement in quality of life since the switch, as I've mentioned in other posts. I still get hot flushes sometimes, but taking a microdose in pill form every day has resulted in more mild side-effects and reduced fatigue, as well as avoiding those 2–3 sick days after every monthly shot that you mentioned and the swelling and rash around the injection site.
I hope your experience is similar. Best of luck!