The study was done with mice. But the quote pertained to humans.
https://www.sciencedirect.com/science/article/pii/S1063458418314730#:~:text=C%2Dreactive%20protein%20(CRP)
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There is evidence that inflammatory biomarkers are elevated in osteoarthritis in humans. The title of the following link is: Inflammatory Biomarkers in Osteoarthritis
"In recent years, there has been a large shift in the understanding of OA as a “wear and tear” disease to an inflammatory disease."
https://pmc.ncbi.nlm.nih.gov/articles/PMC4630669/#:~:text=SF%20levels%20of%20IL%2D6,of%20healthy%20controls(94).
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My personal experience with arthritis is the following:
I developed degenerative osteoarthritis in one knee caused by a sports injury in high school. At the age of 25, I was told that I needed a knee replacement but I had to wait until I was 60 years old to do a knee replacement.
An autoimmune inflammatory arthritis called "reactive arthritis" was diagnosed when I was 32 years old. This inflammatory arthritis liked to attack my spine. However, the inflammation wasn't confined to my spine.
https://www.niams.nih.gov/health-topics/reactive-arthritis
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PMR was diagnosed when I was 52. When PMR was diagnosed, I had shoulder pain that hurt so much that I couldn't lift my arms. I also had "generalized" body pain but I told my rheumatologist that some of the places that hurt were always painful. The shoulder pain was something new and the acute onset and high ESR and CRP along with a rapid response to prednisone was the basis for diagnosing PMR. The rapid response to prednisone alone wasn't diagnostic of PMR because I would say my reactive arthritis flares responded faster to prednisone than PMR did. I never needed to take Prednisone on a long term basis to treat flares of reactive arthritis. However, my rheumatologist said reactive arthritis wasn't treated with prednisone.
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Now I have severe lumbar spinal stenosis that is called "degenerative osteoarthritis" but my spine was where my autoimmune reactive arthritis liked to attack the most. When spinal stenosis was diagnosed, I had acute onset neurological changes along with radicular leg pain (sciatica). An MRI revealed the severe spinal stenosis. I told a spine surgeon that I didn't know I had a "bad back." The surgeon said the kind of damage I had didn't happen overnight. He asked me if I ever had back pain but I said I didn't have any pain when I took prednisone.
I now have arthritis everywhere they look. My shoulders don't hurt anymore and seem to be unscathed. I don't think I have any arthritis in my shoulders.
Good research.