Testosterone recovery after ADT

Posted by scottbeammeup @scottbeammeup, Oct 16 7:41am

I'm ending Orgovyx this month. I want to do whatever I can afterward to recover testosterone to my pre-ADT level of 650.

I know not to take TRT replacement therapy immediately or it will prevent my body from making testosterone naturally. Several people at my gym have recommended the following supplements for getting my T to return faster and possibly to a higher level.

Does anyone know about these: Zinc, Horny Goat Weed, DHEA. My own internet research seems to be mixed on these.

Thanks

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@scottbeammeup

Is 770 really high? My T, without TRT, before treatment was 620. I thought normal was 300-1,000?

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if you’ve had cancer and have a high Gleason (above 7) then you have to be careful about high testosterone. it can sneak up on you and result in spread. PSA tests regularly. Many people fall in the 400-500 range, 770 is higher than most people get.

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Appreciate the comments and yes, I need to monitor PSA regularly. My Gleason scores were 3+3, 3+4, 4+3, Decipher was intermediate. My urologist said at my last visit if PSA increases any more he will probably want to repeat the PSMA. My next consultation with RO is not until April, unless there is a need for it sooner; they also get my bloodwork results.

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@jeffmarc

if you’ve had cancer and have a high Gleason (above 7) then you have to be careful about high testosterone. it can sneak up on you and result in spread. PSA tests regularly. Many people fall in the 400-500 range, 770 is higher than most people get.

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Interesting. So, assuming my T comes back at all after ADT, is there some way to regulate it to stay within normal range but not go so high that it's cause for concern?

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@scottbeammeup

Interesting. So, assuming my T comes back at all after ADT, is there some way to regulate it to stay within normal range but not go so high that it's cause for concern?

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I don’t think most people have to regulate it, when yours comes back, I doubt it will be above 600. Even if it is above 400 though you should be getting regular PSA test to make sure it doesn’t come back. I was hearing from a guy two weeks ago who was talking about the fact that he took a couple of vacations from ADT and he now has multiple metastasis throughout his body. He was a Gleason nine, so Gleason is a factor, but even with a lower Gleason score, you need to be careful.

I suspect if you took monthly test for six or nine months and then went to bimonthly and then every quarter you could feel comfortable that it’s being watched for recurrence.

See what your doctor has to say, hopefully you have an informed oncologist you are working with.

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@jeffmarc

I don’t think most people have to regulate it, when yours comes back, I doubt it will be above 600. Even if it is above 400 though you should be getting regular PSA test to make sure it doesn’t come back. I was hearing from a guy two weeks ago who was talking about the fact that he took a couple of vacations from ADT and he now has multiple metastasis throughout his body. He was a Gleason nine, so Gleason is a factor, but even with a lower Gleason score, you need to be careful.

I suspect if you took monthly test for six or nine months and then went to bimonthly and then every quarter you could feel comfortable that it’s being watched for recurrence.

See what your doctor has to say, hopefully you have an informed oncologist you are working with.

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Yes, ADT ends soon and then the plan is quarterly PSA tests for two years, then twice a year for three years, then once a year after that, assuming it doesn't come back. My oncologist told me the stats show 80% chance of being BCR-free after five years and 70% after 10. However, I think the odds are actually higher because some people die of other things during that time period so aren't counted in the stats. Still, if I can get even a few years without having to go back on ADT it will be a win.

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Here's mine (see attached clinical history).

A lot of factors go into recovery of T, age, baseline, which agent you used...

I have not. nor considered using supplements.

I have read some articles that may indicate exercise may play a role. I'm pretty active but that's not necessarily a correlation.

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